ABSENCE OF HPV-16 AND HPV-18 DNA IN BREAST-CANCER

被引：64

作者：

WREDE, D

LUQMANI, YA

COOMBES, RC

VOUSDEN, KH

机构：

[1] SAMARITAN HOSP WOMEN,DEPT GYNAECOL ONCOL,LONDON NW1 5YE,ENGLAND

[2] CHARING CROSS HOSP,DEPT MED ONCOL,LONDON W6 8RF,ENGLAND

来源：

BRITISH JOURNAL OF CANCER | 1992年 / 65卷 / 06期

关键词：

D O I：

10.1038/bjc.1992.186

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The finding that human papillomavirus (HPV) genes can immortalise breast epithelial cells has led to suggestions that HPV could be involved in the pathogenesis of breast cancer. Using the polymerase chain reaction (PCR) we have been unable to demonstrate the presence of HPV DNA in a series of 80 breast carcinomas.

引用

收藏

页码：891 / 894

页数：4

相关论文

共 14 条

[1] HUMAN PAPILLOMA-VIRUS DNAS IMMORTALIZE NORMAL HUMAN MAMMARY EPITHELIAL-CELLS AND REDUCE THEIR GROWTH-FACTOR REQUIREMENTS [J].

BAND, V ;

ZAJCHOWSKI, D ;

KULESA, V ;

SAGER, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (01) :463-467

[2] LOSS OF P53 PROTEIN IN HUMAN PAPILLOMAVIRUS TYPE-16 E6-IMMORTALIZED HUMAN MAMMARY EPITHELIAL-CELLS [J].

BAND, V ;

DECAPRIO, JA ;

DELMOLINO, L ;

KULESA, V ;

SAGER, R .

JOURNAL OF VIROLOGY, 1991, 65 (12) :6671-6676

[3] HPV16 E6-PROTEINS AND E7-PROTEINS COOPERATE TO IMMORTALIZE HUMAN FORESKIN KERATINOCYTES [J].

HAWLEYNELSON, P ;

VOUSDEN, KH ;

HUBBERT, NL ;

LOWY, DR ;

SCHILLER, JT .

EMBO JOURNAL, 1989, 8 (12) :3905-3910

[4] IMMORTALIZATION AND ALTERED DIFFERENTIATION OF HUMAN KERATINOCYTES INVITRO BY THE E6 AND E7 OPEN READING FRAMES OF HUMAN PAPILLOMAVIRUS TYPE-18 [J].

HUDSON, JB ;

BEDELL, MA ;

MCCANCE, DJ ;

LAIMINS, LA .

JOURNAL OF VIROLOGY, 1990, 64 (02) :519-526

[5] EXPRESSION OF THE PS2 GENE IN NORMAL, BENIGN AND NEOPLASTIC HUMAN STOMACH [J].

LUQMANI, Y ;

BENNETT, C ;

PATERSON, I ;

CORBISHLEY, CM ;

RIO, MC ;

CHAMBON, P ;

RYALL, G .

INTERNATIONAL JOURNAL OF CANCER, 1989, 44 (05) :806-812

[6]

MUNGER K, 1989, J VIROL, V63, P4417

[7]

OSTROW RS, 1987, CANCER, V59, P429, DOI 10.1002/1097-0142(19870201)59:3<429::AID-CNCR2820590313>3.0.CO

[8]

2-1

[9] ENZYMATIC AMPLIFICATION OF BETA-GLOBIN GENOMIC SEQUENCES AND RESTRICTION SITE ANALYSIS FOR DIAGNOSIS OF SICKLE-CELL ANEMIA [J].

SAIKI, RK ;

SCHARF, S ;

FALOONA, F ;

MULLIS, KB ;

HORN, GT ;

ERLICH, HA ;

ARNHEIM, N .

SCIENCE, 1985, 230 (4732) :1350-1354

[10] THE USE OF GENERAL PRIMERS IN THE POLYMERASE CHAIN-REACTION PERMITS THE DETECTION OF A BROAD-SPECTRUM OF HUMAN PAPILLOMAVIRUS GENOTYPES [J].

SNIJDERS, PJF ;

VANDENBRULE, AJC ;

SCHRIJNEMAKERS, HFJ ;

SNOW, G ;

MEIJER, CJLM ;

WALBOOMERS, JMM .

JOURNAL OF GENERAL VIROLOGY, 1990, 71 :173-181