NON-PANCREATIC-TYPE HYPERAMYLASEMIA ASSOCIATED WITH PANCREATIC CANCER

被引:26
作者
SHIMAMURA, J [1 ]
FRIDHANDLER, L [1 ]
BERK, JE [1 ]
机构
[1] UNIV CALIF IRVINE, DEPT MED, DIV GASTROENTEROL, IRVINE, CA USA
来源
AMERICAN JOURNAL OF DIGESTIVE DISEASES | 1976年 / 21卷 / 04期
关键词
D O I
10.1007/BF01071849
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Isoamylase analysis of the serum and urine of a patient with anaplastic spindle cell carcinoma of the pancreas revealed that virtually all serum amylase and almost all urine amylase behaved chromatographically as the salivary (S) type. The serum and urine amylases were bound by a substance derived from a macroamylase complex which bound only S amylase and lacked any affinity for pancreatitis (P) type amylase. The ratio of amylase to creatinine clearance was markedly increased (12.5%) without evidence of acute pancreatitis at autopsy, and despite the presence of only a minute amount of P-type isoamylase in the serum.
引用
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页码:340 / 345
页数:6
相关论文
共 33 条
[11]  
FRIDHANDLER L, 1974, CLIN CHEM, V20, P22
[12]  
FRIDHANDLER L, 1974, CLIN CHEM, V20, P547
[13]  
FRIDHANDLER L, 1972, CLIN CHEM, V18, P1493
[14]  
FRIDHANDLER L, 1971, CLIN CHEM, V17, P423
[15]  
FRIDHANDLER L, 1970, CLIN CHEM, V16, P911
[16]  
FRIDHANDLER L, 1974, CLIN CHEM, V20, P26
[17]  
GASSER P., 1959, HELVETICA MED ACTA, V26, P687
[18]  
HARADA K, 1971, MEDICINE BIOLOGY, V82, P155
[19]  
KAMARYT J, 1969, Z KLIN CHEM KLIN BIO, V7, P51
[20]   ENHANCEMENT OF AMYLASE-CREATININE CLEARANCE RATIO IN DISORDERS OTHER THAN ACUTE-PANCREATITIS [J].
LEVINE, RI ;
GLAUSER, FL ;
BERK, JE .
NEW ENGLAND JOURNAL OF MEDICINE, 1975, 292 (07) :329-332