ENHANCED ENANTIOSELECTIVITY OF THE LIPASE-CATALYZED HYDROLYSIS BY THE ADDITION OF A CATALYTIC AMOUNT OF AN AMINO ALCOHOL

被引：33

作者：

ITOH, T ^{[1
]}

OHIRA, E ^{[1
]}

TAKAGI, Y ^{[1
]}

NISHIYAMA, S ^{[1
]}

NAKAMURA, K ^{[1
]}

机构：

[1] KYOTO UNIV, INST CENT RES, UJI, KYOTO 611, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1991年 / 64卷 / 02期

关键词：

D O I：

10.1246/bcsj.64.624

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

L-Methioninol (L-MetOH) was discovered to be an effective additive for improving the enantioselectivity of lipase-catalyzed hydrolysis. It was found that L-MetOH accelerated the enzyme-catalyzed hydrolysis of (R)-3-acetoxybutyronitrile (1) and inhibited that of (S)-1.

引用

页码：624 / 627

页数：4

共 70 条

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