ENHANCED ENANTIOSELECTIVITY OF THE LIPASE-CATALYZED HYDROLYSIS BY THE ADDITION OF A CATALYTIC AMOUNT OF AN AMINO ALCOHOL

被引：33

作者：

ITOH, T ^{[1
]}

OHIRA, E ^{[1
]}

TAKAGI, Y ^{[1
]}

NISHIYAMA, S ^{[1
]}

NAKAMURA, K ^{[1
]}

机构：

[1] KYOTO UNIV, INST CENT RES, UJI, KYOTO 611, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1991年 / 64卷 / 02期

关键词：

D O I：

10.1246/bcsj.64.624

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

L-Methioninol (L-MetOH) was discovered to be an effective additive for improving the enantioselectivity of lipase-catalyzed hydrolysis. It was found that L-MetOH accelerated the enzyme-catalyzed hydrolysis of (R)-3-acetoxybutyronitrile (1) and inhibited that of (S)-1.

引用

页码：624 / 627

页数：4

共 70 条

[11] BIOCATALYTIC RESOLUTIONS OF ALPHA-METHYLENE-BETA-HYDROXY ESTERS AND KETONES
BURGESS, K
JENNINGS, LD
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (04) : 1138 - 1139
[12] QUANTITATIVE-ANALYSES OF BIOCHEMICAL KINETIC RESOLUTION OF ENANTIOMERS .2. ENZYME-CATALYZED ESTERIFICATIONS IN WATER ORGANIC-SOLVENT BIPHASIC SYSTEMS
CHEN, CS
WU, SH
GIRDAUKAS, G
SIH, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (09) : 2812 - 2817
[13] GENERAL-ASPECTS AND OPTIMIZATION OF ENANTIOSELECTIVE BIOCATALYSIS IN ORGANIC-SOLVENTS - THE USE OF LIPASES
CHEN, CS
SIH, CJ
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1989, 28 (06): : 695 - 707
[14] QUANTITATIVE-ANALYSES OF BIOCHEMICAL KINETIC RESOLUTIONS OF ENANTIOMERS
CHEN, CS
FUJIMOTO, Y
GIRDAUKAS, G
SIH, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (25) : 7294 - 7299
[15] ENZYME CATALYZED ASYMMETRIC HYDROLYSIS OF CHLORAL ACETYL METHYL ACETAL
CHENEVERT, R
DESJARDINS, M
GAGNON, R
[J]. CHEMISTRY LETTERS, 1990, (01) : 33 - 34
[16] CROUT DHG, 1989, MODERN SYNTHETIC MET, P1
[17] NUCLEAR MAGNETIC-RESONANCE ENANTIOMER REAGENTS - CONFIGURATIONAL CORRELATIONS VIA NUCLEAR MAGNETIC-RESONANCE CHEMICAL-SHIFTS OF DIASTEREOMERIC MANDELATE, O-METHYLMANDELATE, AND ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETATE (MTPA) ESTERS
DALE, JA
MOSHER, HS
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (02) : 512 - 519
[18] ENZYME-CATALYZED ASYMMETRIZATION OF BIS(HYDROXYMETHYL)-TETRAHYDROFURANS
ESTERMANN, H
PRASAD, K
SHAPIRO, MJ
REPIC, O
HARDTMANN, GE
BOLSTERLI, JJ
WALKINSHAW, MD
[J]. TETRAHEDRON LETTERS, 1990, 31 (04) : 445 - 448
[19] A NOVEL AND EFFICIENT SYNTHESIS OF (+)- AND (-)-TRANS-2-AMINOCYCLOHEXANOL BY ENZYMATIC-HYDROLYSIS
FABER, K
HONIG, H
SEUFERWASSERTHAL, P
[J]. TETRAHEDRON LETTERS, 1988, 29 (16) : 1903 - 1904
[20] BIOCATALYTIC RESOLUTION OF LONG-CHAIN 3-HYDROXYALKANOIC ESTERS
FEICHTER, C
FABER, K
GRIENGL, H
[J]. TETRAHEDRON LETTERS, 1989, 30 (05) : 551 - 552

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