The combined results of analytical, numerical, and laboratory studies are used in examining the kinetic behavior of sedimentation in well-mixed systems. The rate of mass removal of solids, dC/dt, as a function of mass concentration C, can be described as the sum of three power laws, dC/dt equals minus B//d//sC**2**. **3-B//s//hC**1**. **9-B//bC**1**. **3, each term of which corresponds to a particular coagulation mechanism: differential settling, shear, and Brownian motion. Empirical relationships for the coefficients B//d//s, B//s//h, and B//b as a function of system parameters are provided.