METHOTREXATE ANALOGS .21. DIVERGENT INFLUENCE OF ALKYL CHAIN-LENGTH ON THE DIHYDROFOLATE-REDUCTASE AFFINITY AND CYTO-TOXICITY OF METHOTREXATE MONOESTERS

被引：42

作者：

ROSOWSKY, A

FORSCH, RA

YU, CS

LAZARUS, H

BEARDSLEY, GP

机构：

[1] HARVARD UNIV,SCH MED,DEPT PHARMACOL,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,DEPT PATHOL,BOSTON,MA 02115

[3] HARVARD UNIV,SCH MED,DEPT PEDIAT,BOSTON,MA 02115

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1984年 / 27卷 / 05期

关键词：

D O I：

10.1021/jm00371a009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：605 / 609

页数：5

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