FAMILIAL SCHIZENCEPHALY

被引：40

作者：

HILBURGER, AC

WILLIS, JK

BOULDIN, E

HENDERSONTILTON, A

机构：

[1] Department of Psychiatry and Neurology, Tulane University Medical Center, New Orleans

来源：

BRAIN & DEVELOPMENT | 1993年 / 15卷 / 03期

关键词：

BRAIN MALFORMATION; SCHIZENCEPHALY; FAMILIAL;

D O I：

10.1016/0387-7604(93)90072-G

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Schizencephaly is a brain malformation characterized by infolding of cortical gray matter along a hemispheric cleft near the primary cerebral fissures. Although the etiology is unknown, genetic counseling has not been advocated because of its sporadic occurrence. We describe a family with two affected siblings. Both cases were characterized by hemiparesis, lack of gestational or postnatal complications, and diagnostic radiologic findings. We mise the possibility of a genetic etiology in some cases of schizencephaly and suggest a re-examination of the need for genetic counseling.

引用

页码：234 / 236

页数：3

共 12 条

[1]

ALVEREZ LA, 1986, NEUROLOGY, V36, P489

[2]

BARTH PG, 1992, AM J NEURORADIOL, V13, P104

[3] CONGENITAL HYDROCEPHALUS AND EYE ABNORMALITIES WITH SEVERE DEVELOPMENTAL BRAIN DEFECTS - WARBURGS SYNDROME [J].