PROTEIN-KINASE-C DIRECTLY PHOSPHORYLATES THE INSULIN-RECEPTOR INVITRO AND REDUCES ITS PROTEIN-TYROSINE KINASE-ACTIVITY

被引：270

作者：

BOLLAG, GE ^{[1
]}

ROTH, RA ^{[1
]}

BEAUDOIN, J ^{[1
]}

MOCHLYROSEN, D ^{[1
]}

KOSHLAND, DE ^{[1
]}

机构：

[1] STANFORD UNIV,MED CTR,SCH MED,DEPT PHARMACOL,STANFORD,CA 94305

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1986年 / 83卷 / 16期

关键词：

D O I：

10.1073/pnas.83.16.5822

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5822 / 5824

页数：3

共 24 条

[11] KAHN CR, 1985, ANNU REV MED, V36, P429
[12] KIKKAWA U, 1982, J BIOL CHEM, V257, P13341
[13] PHORBOL ESTER INHIBITION OF HORMONAL INDUCTION OF TYROSINE AMINOTRANSFERASE
KOONTZ, JW
GOODMAN, S
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 131 (02) : 815 - 820
[14] PURIFICATION AND CHARACTERIZATION OF A CA-2+/CALMODULIN-DEPENDENT PROTEIN-KINASE FROM RAT-BRAIN
KURET, J
SCHULMAN, H
[J]. BIOCHEMISTRY, 1984, 23 (23) : 5495 - 5504
[15] INSULIN-RECEPTOR TYROSINE KINASE IS DEFECTIVE IN SKELETAL-MUSCLE OF INSULIN-RESISTANT OBESE MICE
LEMARCHANDBRUSTEL, Y
GREMEAUX, T
BALLOTTI, R
VANOBBERGHEN, E
[J]. NATURE, 1985, 315 (6021) : 676 - 679
[16] ASSOCIATION OF PHORBOL ESTER-INDUCED HYPERPHOSPHORYLATION AND REVERSIBLE REGULATION OF TRANSFERRIN MEMBRANE-RECEPTORS IN HL60 CELLS
MAY, WS
JACOBS, S
CUATRECASAS, P
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (07): : 2016 - 2020
[17] INSULIN ACTION IS BLOCKED BY A MONOCLONAL-ANTIBODY THAT INHIBITS THE INSULIN-RECEPTOR KINASE
MORGAN, DO
HO, L
KORN, LJ
ROTH, RA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (02) : 328 - 332
[18] THE ROLE OF PROTEIN KINASE-C IN CELL-SURFACE SIGNAL TRANSDUCTION AND TUMOR PROMOTION
NISHIZUKA, Y
[J]. NATURE, 1984, 308 (5961) : 693 - 698
[19] HOW INSULIN RESISTANT ARE PATIENTS WITH NONINSULIN-DEPENDENT DIABETES-MELLITUS
REAVEN, GM
CHEN, YDI
DONNER, CC
FRAZE, E
HOLLENBECK, CB
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1985, 61 (01) : 32 - 36
[20] INSULIN-RECEPTOR - EVIDENCE THAT IT IS A PROTEIN-KINASE
ROTH, RA
CASSELL, DJ
[J]. SCIENCE, 1983, 219 (4582) : 299 - 301

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