ENANTIOSELECTIVE ORTHO-LITHIATION OF BENZALDEHYDE CHROMIUMTRICARBONYL COMPLEX

被引：47

作者：

ALEXAKIS, A ^{[1
]}

KANGER, T ^{[1
]}

MANGENEY, P ^{[1
]}

ROSEMUNCH, F ^{[1
]}

PERROTEY, A ^{[1
]}

ROSE, E ^{[1
]}

机构：

[1] UNIV PARIS 06,CHIM ORGAN LAB,CNRS,URA 408,F-75252 PARIS 05,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 09期

关键词：

D O I：

10.1016/0957-4166(95)00283-U

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The asymmetric ortho lithiation of benzaldehyde chromiumtricarbonyl complex is performed by in situ temporary protection of the aldehyde functionality with a chiral amide and BuLi as metallating agent. Reaction with an electrophile followed by acidic hydrolysis leeds to the enantiomerically enriched ortho substituted benzaldehyde chromiumtricarbonyl complex.

引用

页码：2135 / 2138

页数：4

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