PARTIAL DIVERSION OF A MUTANT PROINSULIN (B-10 ASPARTIC-ACID) FROM THE REGULATED TO THE CONSTITUTIVE SECRETORY PATHWAY IN TRANSFECTED ATT-20 CELLS

被引：55

作者：

GROSS, DJ

HALBAN, PA

KAHN, CR

WEIR, GC

VILLAKOMAROFF, L

机构：

[1] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DEPT NEUROL,300 LONGWOOD AVE,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,JOSLIN DIABET CTR,EP JOSLIN RES LAB,BOSTON,MA 02115

[3] UNIV GENEVA,CTR MED UNIV,LABS RECH LOUIS JEANTET,CH-1211 GENEVA 4,SWITZERLAND

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 11期

关键词：

D O I：

10.1073/pnas.86.11.4107

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：4107 / 4111

页数：5

共 32 条

[1] SENSITIVE, PRECISE RADIOIMMUNOASSAY OF SERUM-INSULIN RELYING ON CHARCOAL SEPARATION OF BOUND AND FREE HORMONE MOIETIES
ALBANO, JDM
EKINS, RP
TURNER, RC
MARITZ, G
[J]. ACTA ENDOCRINOLOGICA, 1972, 70 (03): : 487 - +
[2] A MUTANT HUMAN PROINSULIN IS SECRETED FROM ISLETS OF LANGERHANS IN INCREASED AMOUNTS VIA AN UNREGULATED PATHWAY
CARROLL, RJ
HAMMER, RE
CHAN, SJ
SWIFT, HH
RUBENSTEIN, AH
STEINER, DF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) : 8943 - 8947
[3] A MUTATION IN THE B-CHAIN CODING REGION IS ASSOCIATED WITH IMPAIRED PROINSULIN CONVERSION IN A FAMILY WITH HYPERPROINSULINEMIA
CHAN, SJ
SEINO, S
GRUPPUSO, PA
SCHWARTZ, R
STEINER, DF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (08) : 2194 - 2197
[4] HIGH-EFFICIENCY TRANSFORMATION OF MAMMALIAN-CELLS BY PLASMID DNA
CHEN, C
OKAYAMA, H
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (08) : 2745 - 2752
[5] PROINSULIN RADIOIMMUNOASSAY IN THE EVALUATION OF INSULINOMAS AND FAMILIAL HYPERPROINSULINEMIA
COHEN, RM
GIVEN, BD
LICINIOPAIXAO, J
PROVOW, SA
RUE, PA
FRANK, BH
ROOT, MA
POLONSKY, KS
TAGER, HS
RUBENSTEIN, AH
[J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1986, 35 (12): : 1137 - 1146
[6] INTERACTION OF ZINC WITH PROINSULIN
FRANK, BH
VEROS, AJ
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1970, 38 (02) : 284 - &
[7] FAMILIAL HYPERPROINSULINEMIA - AUTOSOMAL DOMINANT DEFECT
GABBAY, KH
DELUCA, K
FISHER, JN
MAKO, ME
RUBENSTEIN, AH
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1976, 294 (17) : 911 - 915
[8] DIFFERENCES IN NATURE OF INTERACTION OF INSULIN AND PROINSULIN WITH ZINC
GRANT, PT
FRANK, BH
COOMBS, TL
[J]. BIOCHEMICAL JOURNAL, 1972, 126 (02) : 433 - &
[9] OXIDATION OF RAT INSULIN-II, BUT NOT I, LEADS TO ANOMALOUS ELUTION PROFILES UPON HPLC ANALYSIS OF INSULIN-RELATED PEPTIDES
GROSS, D
SKVORAK, A
HENDRICK, G
WEIR, G
VILLAKOMAROFF, L
HALBAN, P
[J]. FEBS LETTERS, 1988, 241 (1-2) : 205 - 208
[10] GROSS DJ, 1988, DIABETES S1, V37, pA48

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