INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE BY MEVINOLIN IN FAMILIAL HYPERCHOLESTEROLEMIA HETEROZYGOTES - EFFECTS ON CHOLESTEROL BALANCE

被引：142

作者：

GRUNDY, SM ^{[1
]}

BILHEIMER, DW ^{[1
]}

机构：

[1] UNIV TEXAS, HLTH SCI CTR, CTR HUMAN NUTR, DALLAS, TX 75235 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1984年 / 81卷 / 08期

关键词：

D O I：

10.1073/pnas.81.8.2538

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：2538 / 2542

页数：5

共 23 条

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[2] BERGMANN KV, 1979, GASTROENTEROLOGY, V77, P1183
[3] MEVINOLIN AND COLESTIPOL STIMULATE RECEPTOR-MEDIATED CLEARANCE OF LOW-DENSITY LIPOPROTEIN FROM PLASMA IN FAMILIAL HYPERCHOLESTEROLEMIA HETEROZYGOTES
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[4] BROWN MS, 1978, J BIOL CHEM, V253, P1121
[5] ILEAL BYPASS IN PATIENTS WITH HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS - PRELIMINARY REPORT ON THERAPEUTIC POTENTIAL
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[6] USEFULNESS OF CHROMIC OXIDE AS AN INTERNAL STANDARD FOR BALANCE STUDIES IN FORMULA-FED PATIENTS AND FOR ASSESSMENT OF COLONIC FUNCTION
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[J]. JOURNAL OF CLINICAL INVESTIGATION, 1968, 47 (01) : 127 - &
[7] INHIBITION OF CHOLESTEROL-SYNTHESIS INVITRO AND INVIVO BY ML-236A AND ML-236B, COMPETITIVE INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE
ENDO, A
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[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 77 (01): : 31 - 36
[8] LOW-DENSITY LIPOPROTEIN PATHWAY AND ITS RELATION TO ATHEROSCLEROSIS
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BROWN, MS
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1977, 46 : 897 - 930
[9] GOLDSTEIN JL, 1979, J BIOL CHEM, V254, P5403
[10] GOODMAN DS, 1980, J LIPID RES, V21, P699

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