THE FORMATION OF PROTEIN DISULFIDE BONDS

被引：86

作者：

FREEDMAN, RB

机构：

[1] RB Freedman, Research School of Biosciences, Biological Laboratory, Canterbury, 7NJ

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 01期

关键词：

D O I：

10.1016/0959-440X(95)80013-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The past year has provided more detail on the formation of native disulphide bonds during protein folding at biosynthesis and has identified important cellular factors in the oxidative folding compartments, namely the eukaryotic endoplasmic reticulum and the bacterial periplasm. This information has enabled traditional in vitro refolding studies to be re-evaluated and their relevance as models for folding in the cell to be established.

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页码：85 / 91

页数：7

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