1-(2,3-DIDEOXY-BETA-D-GLYCERO-PENT-2-ENOFURANOSYL)THYMINE - A HIGHLY POTENT AND SELECTIVE ANTI-HIV AGENT

被引：223

作者：

MANSURI, MM ^{[1
]}

STARRETT, JE ^{[1
]}

GHAZZOULI, I ^{[1
]}

HITCHCOCK, MJM ^{[1
]}

STERZYCKI, RZ ^{[1
]}

BRANKOVAN, V ^{[1
]}

LIN, TS ^{[1
]}

AUGUST, EM ^{[1
]}

PRUSOFF, WH ^{[1
]}

SOMMADOSSI, JP ^{[1
]}

MARTIN, JC ^{[1
]}

机构：

[1] BRISTOL MYERS CO,DIV PHARMACEUT RES & DEV,DEPT VIROL,WALLINGFORD,CT 06492

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 02期

关键词：

D O I：

10.1021/jm00122a029

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：461 / 466

页数：6

共 48 条

[1] ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID .34. TERMINATION OF CHAIN GROWTH BY A 2',3'-DIDEOXYRIBONUCLEOTIDE
ATKINSON, MR
DEUTSCHER, MP
KORNBERG, A
RUSSELL, AF
MOFFATT, JG
[J]. BIOCHEMISTRY, 1969, 8 (12) : 4897 - +
[2] BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO
BABA, M
PAUWELS, R
HERDEWIJN, P
DECLERCQ, E
DESMYTER, J
VANDEPUTTE, M
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 142 (01) : 128 - 134
[3] SELECTIVE-INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) BY 3'-AZIDO-2',3'-DIDEOXYGUANOSINE INVITRO
BABA, M
PAUWELS, R
BALZARINI, J
HERDEWIJN, P
DECLERCQ, E
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 145 (03) : 1080 - 1086
[4] COMPARATIVE INHIBITORY EFFECTS OF SURAMIN AND OTHER SELECTED COMPOUNDS ON THE INFECTIVITY AND REPLICATION OF HUMAN T-CELL LYMPHOTROPIC VIRUS (HTLV-III) LYMPHADENOPATHY-ASSOCIATED VIRUS (LAV)
BALZARINI, J
MITSUYA, H
DECLERCQ, E
BRODER, S
[J]. INTERNATIONAL JOURNAL OF CANCER, 1986, 37 (03) : 451 - 457
[5] POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE
BALZARINI, J
PAUWELS, R
HERDEWIJN, P
DECLERCQ, E
COONEY, DA
KANG, GJ
DALAL, M
JOHNS, DG
BRODER, S
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (02) : 735 - 742
[6] BALZARINI J, 1987, MOL PHARMACOL, V32, P162
[7] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS)
BARRESINOUSSI, F
CHERMANN, JC
REY, F
NUGEYRE, MT
CHAMARET, S
GRUEST, J
DAUGUET, C
AXLERBLIN, C
VEZINETBRUN, F
ROUZIOUX, C
ROZENBAUM, W
MONTAGNIER, L
[J]. SCIENCE, 1983, 220 (4599) : 868 - 871
[8] A PATHOGENIC RETROVIRUS (HTLV-III) LINKED TO AIDS
BRODER, S
GALLO, RC
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (20) : 1292 - 1297
[9] BRODER S, 1985, ANNU REV IMMUNOL, V3, P321, DOI 10.1146/annurev.iy.03.040185.001541
[10] CHANDRA P, 1985, CANCER RES, V45, P4677

← 1 2 3 4 5 →