CHARACTERIZATION AND TRYPSIN-INHIBITOR ACTIVITY OF PROANTHOCYANIDINS FROM VICIA-FABA

被引：35

作者：

HELSPER, JPFG

KOLODZIEJ, H

HOOGENDIJK, JM

VANNOREL, A

机构：

[1] DLO, CTR PLANT BREEDING & REPROD RES, CPRO, 6700 AA WAGENINGEN, NETHERLANDS

[2] FREE UNIV BERLIN, INST PHARMAZEUT BIOL, W-1000 BERLIN 33, GERMANY

来源：

PHYTOCHEMISTRY | 1993年 / 34卷 / 05期

关键词：

VICIA-FABA; LEGUMINOSAE; FABA BEANS; PROANTHOCYANIDINS; TRYPSIN INHIBITOR ACTIVITY;

D O I：

10.1016/0031-9422(91)80011-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In a chemical investigation epicatechin, epigallocatechin, the procyanidins B-1, B-3 and B-4, and the prodelphinidins gallocatechin-(4alpha,8)-catechin, gallocatechin-(4alpha,8)-epicatechin and gallocatechin-(4alpha,8)-epigallocatechin have been isolated from the testa of faba beans and characterized by means of spectroscopic methods. Proanthocyanidin samples were compared for their trypsin inhibitory activity. The results suggest that the degree of polymerization, the number of phenolic hydroxyl groups and the 2,3-stereochemistry of the constituent units affect remarkably the strength of the inhibition.

引用

页码：1255 / 1260

页数：6

共 21 条

[1] PLANT PROANTHOCYANIDINS .6. CHIROPTICAL STUDIES .95. CIRCULAR-DICHROISM OF PROCYANIDINS
BARRETT, MW
KLYNE, W
SCOPES, PM
FLETCHER, AC
PORTER, LJ
HASLAM, E
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1979, (10): : 2375 - 2377
[2] SYNTHESIS OF CONDENSED TANNINS .1. STEREOSELECTIVE AND STEREOSPECIFIC SYNTHESES OF OPTICALLY PURE 4-ARYLFLAVAN-3-OLS, AND ASSESSMENT OF THEIR ABSOLUTE STEREOCHEMISTRY AT C-4 BY MEANS OF CIRCULAR-DICHROISM
BOTHA, JJ
YOUNG, DA
FERREIRA, D
ROUX, DG
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (04): : 1213 - 1219
[3] BIOLOGICAL AND CHEMICAL INVESTIGATION OF DRAGONS BLOOD FROM CROTON SPECIES OF SOUTH-AMERICA .1. POLYPHENOLIC COMPOUNDS FROM CROTON-LECHLERI
CAI, Y
EVANS, FJ
ROBERTS, MF
PHILLIPSON, JD
ZENK, MH
GLEBA, YY
[J]. PHYTOCHEMISTRY, 1991, 30 (06) : 2033 - 2040
[4] PLANT PROANTHOCYANIDINS .3. CONFORMATIONAL AND CONFIGURATIONAL STUDIES OF NATURAL PROCYANIDINS
FLETCHER, AC
PORTER, LJ
HASLAM, E
GUPTA, RK
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1977, (14): : 1628 - 1637
[5] PRODELPHINIDIN POLYMERS - DEFINITION OF STRUCTURAL UNITS
FOO, LY
PORTER, LJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1978, (10): : 1186 - 1190
[6] GRIFFITHS DW, 1979, J SCI FOOD AGR, V30, P458, DOI 10.1002/jsfa.2740300503
[7] HASHIMOTO F, 1989, CHEM PHARM BULL, V37, P3255
[8] HASHIMOTO F, 1989, CHEM PHARM BULL, V37, P77
[9] JANSMAN AJM, 1989, RECENT ADVANCES OF RESEARCH IN ANTINUTRITIONAL FACTORS IN LEGUME SEEDS, P176
[10] KAKADE ML, 1974, CEREAL CHEM, V51, P376

← 1 2 3 →