CHARACTERIZATION AND TRYPSIN-INHIBITOR ACTIVITY OF PROANTHOCYANIDINS FROM VICIA-FABA

被引：35

作者：

HELSPER, JPFG

KOLODZIEJ, H

HOOGENDIJK, JM

VANNOREL, A

机构：

[1] DLO, CTR PLANT BREEDING & REPROD RES, CPRO, 6700 AA WAGENINGEN, NETHERLANDS

[2] FREE UNIV BERLIN, INST PHARMAZEUT BIOL, W-1000 BERLIN 33, GERMANY

来源：

PHYTOCHEMISTRY | 1993年 / 34卷 / 05期

关键词：

VICIA-FABA; LEGUMINOSAE; FABA BEANS; PROANTHOCYANIDINS; TRYPSIN INHIBITOR ACTIVITY;

D O I：

10.1016/0031-9422(91)80011-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In a chemical investigation epicatechin, epigallocatechin, the procyanidins B-1, B-3 and B-4, and the prodelphinidins gallocatechin-(4alpha,8)-catechin, gallocatechin-(4alpha,8)-epicatechin and gallocatechin-(4alpha,8)-epigallocatechin have been isolated from the testa of faba beans and characterized by means of spectroscopic methods. Proanthocyanidin samples were compared for their trypsin inhibitory activity. The results suggest that the degree of polymerization, the number of phenolic hydroxyl groups and the 2,3-stereochemistry of the constituent units affect remarkably the strength of the inhibition.

引用

页码：1255 / 1260

页数：6