AUDITORY EVENT-RELATED POTENTIALS IN OBSTRUCTIVE SLEEP-APNEA - EFFECTS OF TREATMENT WITH NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE

被引:53
作者
RUMBACH, L [1 ]
KRIEGER, J [1 ]
KURTZ, D [1 ]
机构
[1] CHU STRASBOURG,NEUROL CLIN,SERV EXPLORAT FONCT SYST NERVEUX,F-67091 STRASBOURG,FRANCE
来源
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1991年 / 80卷 / 05期
关键词
SLEEP APNEA; EVENT-RELATED POTENTIALS; CONTINUOUS POSITIVE AIRWAY PRESSURE;
D O I
10.1016/0168-5597(91)90094-E
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Event-related potentials (ERPs) were recorded in 47 patients with obstructive sleep apnea (OSA) syndrome prior to and after 6 weeks of treatment with continuous positive airway pressure (CPAP). Compared with a control group, the OSA patients showed ERP abnormalities: lengthened P3 latencies and decreased N2-P3 amplitudes. After 6 weeks of CPAP treatment, there was a highly significant improvement in the abnormal ERPs: the P3 and N2 latencies were shortened, but remained longer than in controls, and the N2-P3 and N1-P2 amplitudes were increased. No correlations could be established with various sleep variables. ERPs may be used as an electrophysiological marker of brain dysfunction; treatment of OSA with CPAP is probably responsible for functional brain modifications. On the other hand, possible relationships between the ERP abnormalities and the neuropsychological disorders observed in OSA remain to be established.
引用
收藏
页码:454 / 457
页数:4
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