2-DIMENSIONAL MAPPING OF N-GLYCOSIDICALLY LINKED OLIGOSACCHARIDES IN GLYCOPROTEINS BY HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS

被引：12

作者：

SUZUKI, S ^{[1
]}

HONDA, S ^{[1
]}

机构：

[1] KINKI UNIV,FAC PHARMACEUT SCI,OSAKA,OSAKA 577,JAPAN

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 1995年 / 14卷 / 06期

关键词：

D O I：

10.1016/0165-9936(95)91621-X

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The recent progress of the biotechnology of glycoproteins has aroused great interest in the functions of the carbohydrate chains. In order to elucidate the structure-function correlation in carbohydrate chains, a convenient method which allows both qualitative and quantitative analyses of the carbohydrate chains is indispensable. This review covers the development of a new method for identifying and quantifying N-glycosidically linked oligosaccharides in glycoproteins, based on two-dimensional mapping by high performance capillary electrophoresis, which has proved to be of potential value for this purpose.

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页码：279 / 288

页数：10

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