EFFECTS OF INDOMETHACIN ON ADHESION FORMATION AFTER REPAIR OF ZONE-II TENDON LACERATIONS IN THE RABBIT

被引：62

作者：

SZABO, RM

YOUNGER, E

机构：

[1] University of California, Davis, Department of Orthopaedic Surgery, Sacramento, CA

来源：

JOURNAL OF HAND SURGERY-AMERICAN VOLUME | 1990年 / 15A卷 / 03期

关键词：

D O I：

10.1016/0363-5023(90)90066-Z

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The flexor digitorum profundus tendon of the second medial toe of the hind foot was completely divided and repaired in zone II in 30 New Zealand white rabbits. Half of the animals received indomethacin solution (1 mg/kg/day) injected subcutaneously 2 hours before operation and daily for 4 weeks. The remaining 15 animals received daily injection of the same volume of saline solution. At 4 weeks the animals were killed and measurements were made of the angular motion of the distal interphalangeal joint and the excursion of the tendon. The animals treated with indomethacin had a greater tendon excursion and angular rotation of the joint than the control animals, implying a suppression of adhesions. © 1990.

引用

页码：480 / 483

页数：4

共 24 条

[11]

Becher, Graham, Cohen, Diegelmann, Intrinsic tendon cell proliferation in tissue culture, The Journal of Hand Surgery, 6 A, pp. 616-619, (1981)

[12]

Gelberman, Manske, VandeBerg, Lesker, Akeson, Flexor tendon healing in vitro: comparative histologic study of rabbit, chicken, dog, and monkey, J Orthop Res, 2, pp. 39-48, (1984)

[13]

Gelberman, Manske, Akeson, Woo, Lundborg, Amiel, Flexor tendon repair, J Orthop Res, 4, pp. 119-128, (1986)

[14]

Graham, Becher, Cohen, Merritt, Diegelmann, Intrinsic tendon fibroplasia: documentation by in vitro studies, J Orthop Res, 1, pp. 251-256, (1984)

[15]

Lundborg, Rank, Experimental studies on cellular mechanisms involved in healing of animal and human flexor tendon in synovial environment, Hand, 12, pp. 3-11, (1985)

[16]

Manske, Gelberman, VandeBerg, Et al., Intrinsic flexor tendon repair: a morphological study in vitro, J Bone Joint Surg, 66 A, pp. 385-396, (1984)

[17]

Manske, Lesker, Histologic evidence of intrinsic flexor tendon repair in various experimental animals, Clin Orthop, 182, pp. 297-304, (1984)

[18]

Potenza, Tendon healing within the flexor digital sheath in the dog, J Bone Joint Surg, 44 A, pp. 49-64, (1964)

[19]

Potenza, Effect of associated trauma on healing of divided tendons, J Trauma, 2, pp. 175-184, (1962)

[20]

Potenza, Evaluation of freeze-dried flexor tendon grafts in the dog, J Hand Surg, 3, pp. 157-162, (1978)

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