RECRUITMENT OF DORSAL COLUMN FIBERS IN SPINAL-CORD STIMULATION - INFLUENCE OF COLLATERAL BRANCHING

被引:109
作者
STRUIJK, JJ
HOLSHEIMER, J
VANDERHEIDE, GG
BOOM, HBK
机构
[1] Biomedical Engineering Division, Department of Electrical Engineering, University of Twente
关键词
D O I
10.1109/10.256423
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An electrical network model of myelinated dorsal column nerve fibers is presented. The effect of electrical stimulation was investigated using both a homogeneous volume conductor and a more realistic model of the spinal cord. An important feature of dorsal column nerve fibers is the presence of myelinated collaterals perpendicular to the rostro-caudal fibers. It was found that transmembrane potentials, due to external monopolar stimulation, at the node at which a collateral is attached, is significantly influenced by the presence of the collateral. It is concluded that both excitation threshold and blocking threshold of dorsal column fibers are decreased up to 50% compared to unbranched fibers.
引用
收藏
页码:903 / 912
页数:10
相关论文
共 35 条