ASYMMETRIC TOTAL SYNTHESIS OF AN A-RING PRECURSOR TO HORMONALLY ACTIVE 1-ALPHA,25-DIHYDROXYVITAMIN-D3

被引:78
作者
POSNER, GH
KINTER, CM
机构
[1] Department of Chemistry, The Johns Hopkins University, Baltimore
关键词
D O I
10.1021/jo00300a001
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
: A new sulfinyl orthoester has been designed and used effectively in one-flask syntheses of dienoate esters from allylic alcohols; this new method as well as a highly stereocontrolled [2 + 4]-cycloaddition are applied to synthesis of lα,25-dihydroxyvitamin D3. © 1990, American Chemical Society. All rights reserved.
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页码:3967 / 3969
页数:3
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