PSYCHOPATHOLOGY IN DRUG-ABUSERS AND THEIR FAMILIES

被引:115
作者
MIRIN, SM
WEISS, RD
GRIFFIN, ML
MICHAEL, JL
机构
[1] HARVARD UNIV, SCH MED, DEPT PSYCHIAT, BOSTON, MA 02115 USA
[2] MCLEAN HOSP, CTR ALCOHOL & DRUG ABUSE TREATMENT, BELMONT, MA 02178 USA
关键词
D O I
10.1016/0010-440X(91)90068-N
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Demographic, clinical, and family pedigree data obtained on 350 hospitalized drug-dependent patients showed that 52% also met DSM-III criteria for alcohol abuse or dependence, while 37% met DSM-III criteria for a concurrent axis I psychiatric disorder other than substance abuse. Cyclothymic disorder was significantly more common among cocaine abusers, while generalized anxiety disorder and panic disorder were more common among sedative-hypnotic abusers. Data on 1,478 first-degree relatives revealed that the prevalence of alcoholism and affective disorder was highly correlated with the occurrence of similar psychopathology in the probands. These findings suggest a relationship between drug of choice and comorbid psychopathology, a role for familial factors in the transmission of these disorders, and the importance of diagnostic subtypes in the evaluation and treatment of substance abusers. © 1991.
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页码:36 / 51
页数:16
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