TRANSLOCATION (12 17)(P11-12 Q11-12) - A RECURRENT PRIMARY REARRANGEMENT IN ACUTE-LEUKEMIA

被引：12

作者：

LIU, HW ^{[1
]}

WAN, SK ^{[1
]}

CHING, LM ^{[1
]}

LIANG, R ^{[1
]}

CHAN, LC ^{[1
]}

机构：

[1] UNIV HONG KONG,DEPT PATHOL,HONG KONG,HONG KONG

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 64卷 / 01期

关键词：

D O I：

10.1016/0165-4608(92)90317-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We identified two patients with acute leukemia in relapse [one lymphoblastic and the other with evidence of mixed lymphoid-myeloid differentiation] with t[12;17][p12;q11] as the primary karyotypic abnormality. There are six previously reported cases of acute leukemia with an identical or similar translocation. To our knowledge, t[12;17] has not been reported in other forms of neoplasia. A review of these cases suggests that t[12;17] carries a poor prognosis.

引用

页码：27 / 29

页数：3

共 13 条

[11] USE OF CONDITIONED MEDIA IN CELL-CULTURE CAN MASK CYTOGENETIC ABNORMALITIES IN ACUTE-LEUKEMIA
SUN, GX
KOEFFLER, HP
GALE, RP
SPARKES, RS
SCHRECK, RR
[J]. CANCER GENETICS AND CYTOGENETICS, 1990, 46 (01) : 107 - 113
[12] FLUORODEOXYURIDINE SYNCHRONIZATION OF BONE-MARROW CULTURES
WEBBER, LM
GARSON, OM
[J]. CANCER GENETICS AND CYTOGENETICS, 1983, 8 (02) : 123 - 132
[13] NEW CHROMOSOMAL TRANSLOCATIONS CORRELATE WITH SPECIFIC IMMUNOPHENOTYPES OF CHILDHOOD ACUTE LYMPHOBLASTIC-LEUKEMIA
WILLIAMS, DL
LOOK, AT
MELVIN, SL
ROBERSON, PK
DAHL, G
FLAKE, T
STASS, S
[J]. CELL, 1984, 36 (01) : 101 - 109

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