SYNTHESIS OF PHYSOPERUVINE (8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-1-OL), NORPHYSOPERUVINE AND DEHYDRO-DERIVATES

被引：21

作者：

JUSTICE, DE ^{[1
]}

MALPASS, JR ^{[1
]}

机构：

[1] UNIV LEICESTER,DEPT CHEM,LEICESTER LE1 7RH,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 18期

关键词：

D O I：

10.1039/p19940002559

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Aminocycloheptanones have been synthesised in high yield from cyclohepta-1,3-diene. These compounds exist mainly as the bicyclic tautomers (8-azabicyclo[3.2.1] octan-1-ol derivatives; the title compounds) as shown by C-13 NMR spectroscopy at low temperatures. 4-Aminocyclohept-2-enones are reactive but show a preference for the monocyclic tautomers; N-benzytoxycarbonyl derivatives of the saturated and unsaturated systems are isolated as the monocyclic tautomers.

引用

页码：2559 / 2564

页数：6

共 22 条

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