EXPRESSION OF THE PS2 GENE IN BREAST-CANCER - A COMPARISON OF PS2 PROTEIN RADIOIMMUNOASSAY AND IMMUNOHISTOCHEMISTRY

被引:9
作者
ROBBINS, PD [1 ]
HAHNEL, E [1 ]
STERRETT, GF [1 ]
HARVEY, J [1 ]
CARRELLO, S [1 ]
HAHNEL, R [1 ]
机构
[1] UNIV WESTERN AUSTRALIA,SIR CHARLES GAIRDNER HOSP,HOSP & UNIV PATHOL SERV,NEDLANDS,WA,AUSTRALIA
关键词
PS2; GENE; RADIOIMMUNOASSAY; IMMUNOHISTOCHEMISTRY; BREAST CANCER;
D O I
10.3109/00313029309066586
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
pS2 expression was studied in a series of 82 primary breast carcinomas using and comparing a radioimmunoassay (RIA) technique and immunohistochemistry (IPOX). There was close correlation of the results obtained with each technique. Accurate and reliable determination of pS2 status in breast cancer can be made on the basis of immunohistochemistry using formalin fixed paraffin embedded sections. Immunohistochemical determination of pS2 status may be used in situations where the RIA technique cannot be applied, i.e. instances when fresh tumor tissue is not available.
引用
收藏
页码:255 / 260
页数:6
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