CHROMOSOME ANALYSIS IN THE MANAGEMENT OF PATIENTS WITH NON-HODGKINS-LYMPHOMA

被引：20

作者：

OFFIT, K

机构：

[1] Departments of Medicine (Lymphoma Service) and Pathology (Cytogenetics Service), Memorial Hospital, Memorial Sloan Kettering Cancer Center, NY

来源：

LEUKEMIA & LYMPHOMA | 1992年 / 7卷 / 04期

关键词：

CYTOGENETICS; MOLECULAR DIAGNOSTICS; CHROMOSOME TRANSLOCATIONS; NON-HODGKINS LYMPHOMA; PROGNOSIS; THERAPY;

D O I：

10.3109/10428199209049778

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Analysis of chromosome abnormalities in non-Hodgkin's lymphoma has stimulated a basic inquiry into the mechanisms of gene deregulation in human tumors. A growing literature has also correlated cytogenetic and molecular genetic features of lymphoma with patient prognosis and other clinical features of the disease. The goal of this report is to review those genetic abnormalities which are currently useful in the clinical management of patients with lymphoma, and to provide a conceptual framework for this growing literature.

引用

页码：275 / 282

页数：8

共 83 条

[1]

Haluska F.G., Tsujimoto Y., Croce C.M., Oncogene activation by chromosome translocation in human malignancy, Annual Review of Genetics, 21, pp. 321-345, (1987)

[2]

Mc Keithan T.W., Molecular biology of non-Hodgkin's lymphomas, Seminars in Oncology, 17, pp. 30-42, (1990)

[3]

Chaganti R.S.K., Koduru P.R.K., Patterns of chromosome breakage in non-Hodgkin's lymphoma: significance to gene alteration in tumorigenesis, Cytogenetics and Cell Genetics, 45, pp. 93-98, (1987)

[4]

Offit K., Chaganti R.S.K., Chromosomal aberrations in non-Hodgkin's lymphoma: biologic and clinical correlations, Hematology/Oncology Clinics of North America, 5, pp. 853-869, (1991)

[5]

Le Beau M.M., Chromosomal abnormalities in non-Hodgkin's lymphomas, Seminars in Oncology, 17, pp. 20-29, (1990)

[6]

Zech L., Haglund V., Nilsson K., Characteristic chromosomal abnormalities in biopsies and lymphoid cell lines from patients with Burkilt and non-Burkitt lymphomas, International Journal of Cancer, 17, pp. 47-56, (1976)

[7]

Manolov G., Manolova Y., Marker band in one chromosome 14 from Burkitts lymphomas, Nature, 237, pp. 33-34, (1972)

[8]

Fukuhara S., Rowley J.D., Chromosome 14 translocations in non-Burkitt lymphomas, International Journal of Cancer, 22, pp. 14-21, (1978)

[9]

Yunis J.J., Oken M., Kaplan M.E., Et al., Distinctive. chromosomal abnormalities in histologic subtypes of non-Hodgkin's lymphoma, New England Journal of Medicine, 307, pp. 1231-1236, (1982)

[10]

Kaneko Y., Variakojis D., Kluskens L., Et al., Lymphoblastic lymphoma: Cytogenetic, pathologic, and immunologic studies, International Journal of Cancer, 30, pp. 273-279, (1982)

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