A 3-YEAR FOLLOW-UP-STUDY OF OCULAR HYPERTENSION BY PATTERN ELECTRORETINOGRAM

被引：23

作者：

ARAI, M ^{[1
]}

YOSHIMURA, N ^{[1
]}

SAKAUE, H ^{[1
]}

CHIHARA, E ^{[1
]}

HONDA, Y ^{[1
]}

机构：

[1] KYOTO UNIV,FAC MED,DEPT OPHTHALMOL,KYOTO 606,JAPAN

来源：

OPHTHALMOLOGICA | 1993年 / 207卷 / 04期

关键词：

PATTERN ELECTRORETINOGRAM; OCULAR HYPERTENSION; STATIC PERIMETRY; GLAUCOMATOUS CHANGE;

D O I：

10.1159/000310431

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

A 3-year following-up study of the pattern electroretinogram (PERG) was performed in 15 eyes of 8 ocular hypertensive (OHT) patients. At first PERG recording, the amplitude of the first positive wave P1 was statistically significantly reduced in the OHT patients compared with age-matched controls (p < 0.05). There was no difference in the amplitude of the second negative wave N2 (p > 0.05). At 40 months, the amplitude of both P1 and N2 decreased and the latency of PI was elongated. Among the changes, the decrease in N2 amplitude was the most drastic (p = 0.0001 compared with the control, p < 0.05, compared with the first recording). Glaucomatous visual field defects developed 5 years after the first PERG recording and 2 years after the reduction in N2 amplitude in 1 patient. Decreased N2 amplitude of the PERG may be an important warning sign predicting the development of glaucoma in OHT patients.

引用

页码：187 / 195

页数：9

共 32 条

[11] CHANGES IN SPATIAL SELECTIVITY OF PATTERN-ERG COMPONENTS WITH STIMULUS CONTRAST [J].