SYNTHESIS OF BIOLOGICALLY-ACTIVE DRIMANES AND HOMODRIMANES FROM (-)-SCLAREOL

被引：74

作者：

BARRERO, AF

MANZANEDA, EA

ALTAREJOS, J

SALIDO, S

RAMOS, JM

SIMMONDS, MSJ

BLANEY, WM

机构：

[1] ROYAL BOT GARDENS,JODRELL LAB,RICHMOND TW9 3AE,SURREY,ENGLAND

[2] UNIV LONDON BIRKBECK COLL,DEPT BIOL,LONDON,ENGLAND

来源：

TETRAHEDRON | 1995年 / 51卷 / 27期

关键词：

D O I：

10.1016/0040-4020(95)00370-N

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three drimanes, polygodial (2), albicanyl acerate (3) and 7-oxo-8,12-drimen-11-al (5), and two homodrimanes, 13,14,15,16-tetranorlabd-7-en-12,17-dial (6) and 7-oxo-13,14,15,16-tetranorlabd-8(17)-en-12-al (7), were synthesized from (-)-sclareol (1), and their antifeedant, antitumor and antimicrobial properties tested. In mast cases, 6 and 7 were found to be more active than 2.

引用

页码：7435 / 7450

页数：16

共 22 条

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