SYNTHESIS AND IMMUNOADJUVANT ACTIVITIES OF 2-ACETAMIDO-5-O-ACETYL-6-O-ACYL-2-DEOXY-3-O-[(R)-2-PROPIONYL-L-ALANYL-D-ISOGLUTAMINE]-D-GLUCOFURANOSES AS POTENTIAL PRODRUG FORMS OF 6-O-ACYL DERIVATIVES OF N-ACETYLMURAMYL DIPEPTIDE

被引：19

作者：

DURETTE, PL ^{[1
]}

DORN, CP ^{[1
]}

FRIEDMAN, A ^{[1
]}

SCHLABACH, A ^{[1
]}

机构：

[1] MERCK SHARP & DOHME,RES LABS,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 09期

关键词：

D O I：

10.1021/jm00351a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1028 / 1033

页数：6

共 38 条

[1]

ALLISON AC, 1979, J RETICULOENDOTH SOC, V26, P619

[2] DISTINCTIVE ADJUVANTICITY OF SYNTHETIC ANALOGS OF MYCOBACTERIAL WATER-SOLUBLE COMPONENTS [J].

AUDIBERT, F ;

CHEDID, L ;

LEFRANCIER, P ;

CHOAY, J .

CELLULAR IMMUNOLOGY, 1976, 21 (02) :243-249

[3]

AZUMA I, 1978, INFECT IMMUN, V20, P600, DOI 10.1128/IAI.20.3.600-607.1978

[4] ADJUVANT ACTIVITY OF MYCOBACTERIAL FRACTIONS - ADJUVANT ACTIVITY OF SYNTHETIC N-ACETYLMURAMYL-DIPEPTIDE AND RELATED COMPOUNDS [J].

AZUMA, I ;

SUGIMURA, K ;

TANIYAMA, T ;

YAMAWAKI, M ;

YAMAMURA, Y ;

KUSUMOTO, S ;

OKADA, S ;

SHIBA, T .

INFECTION AND IMMUNITY, 1976, 14 (01) :18-27

[5] VACCINE AGAINST HUMAN HEPATITIS-B [J].

BUYNAK, EB ;

ROEHM, RR ;

TYTELL, AA ;

BERTLAND, AU ;

LAMPSON, GP ;

HILLEMAN, MR .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1976, 235 (26) :2832-2834

[6] ENHANCEMENT OF NONSPECIFIC IMMUNITY TO KLEBSIELLA-PNEUMONIAE INFECTION BY A SYNTHETIC IMMUNOADJUVANT (N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE) AND SEVERAL ANALOGS [J].

CHEDID, L ;

PARANT, M ;

PARANT, F ;

LEFRANCIER, P ;

CHOAY, J ;

LEDERER, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (05) :2089-2093

[7] MODULATION OF IMMUNE-RESPONSE BY A SYNTHETIC ADJUVANT AND ANALOGS [J].

CHEDID, L ;

AUDIBERT, F ;

LEFRANCIER, P ;

CHOAY, J ;

LEDERER, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (07) :2472-2475

[8] PYROGENICITY OF THE SYNTHETIC ADJUVANT MURAMYL DIPEPTIDE AND 2 STRUCTURAL ANALOGS [J].

DINARELLO, CA ;

ELIN, RJ ;

CHEDID, L ;

WOLFF, SM .

JOURNAL OF INFECTIOUS DISEASES, 1978, 138 (06) :760-767

[9]

DORN CJ, UNPUB

[10] BACTERIAL CELL-WALL CONSTITUENTS .4. SYNTHESIS OF 2-METHYL-[2-ACETAMIDO-4-0-ACETYL-6-0-BENZYL-3-0-(2-BUTENYL)-1,2-DIDEOXY-ALPHA-D-GLUCOPYRANO]-[2,1-D]-2-OXAZOLINE, A VERSATILE INTERMEDIATE FOR THE SYNTHESIS OF COMPLEX OLIGOSACCHARIDES OF BACTERIAL CELL-WALL, HUMAN-MILK, AND BLOOD-GROUP SUBSTANCES [J].

DURETTE, PL ;

MEITZNER, EP .

CARBOHYDRATE RESEARCH, 1981, 89 (02) :279-288

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