SYNTHESIS AND IMMUNOADJUVANT ACTIVITIES OF 2-ACETAMIDO-5-O-ACETYL-6-O-ACYL-2-DEOXY-3-O-[(R)-2-PROPIONYL-L-ALANYL-D-ISOGLUTAMINE]-D-GLUCOFURANOSES AS POTENTIAL PRODRUG FORMS OF 6-O-ACYL DERIVATIVES OF N-ACETYLMURAMYL DIPEPTIDE

被引：19

作者：

DURETTE, PL ^{[1
]}

DORN, CP ^{[1
]}

FRIEDMAN, A ^{[1
]}

SCHLABACH, A ^{[1
]}

机构：

[1] MERCK SHARP & DOHME,RES LABS,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 09期

关键词：

D O I：

10.1021/jm00351a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1028 / 1033

页数：6

共 38 条

[11]

DURETTE PL, UNPUB

[12] MINIMAL STRUCTURAL REQUIREMENTS FOR ADJUVANT ACTIVITY OF BACTERIAL PEPTIDOGLYCAN DERIVATIVES [J].

ELLOUZ, F ;

ADAM, A ;

CIORBARU, R ;

LEDERER, E .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1974, 59 (04) :1317-1325

[13]

FISHER RA, 1954, STATISTICAL METHODS

[14]

FREUND J, 1956, Bibl Tuberc, P130

[15] THE ANOMERIC CONFIGURATION OF THE IMMUNOSTIMULANT N-ACETYLMURAMOYL-DIPEPTIDE AND SOME OF ITS DERIVATIVES [J].

HALLS, TDJ ;

RAJU, MS ;

WENKERT, E ;

ZUBER, M ;

LEFRANCIER, P ;

LEDERER, E .

CARBOHYDRATE RESEARCH, 1980, 81 (01) :173-176

[16] REACTIONS OF 2-ACYLOXYISOBUTYRYL HALIDES WITH NUCLEOSIDES .6. SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME 3'-ACYL DERIVATIVES OF 2,2'-ANHYDRO-1-(BETA-D-ARABINOFURANOSYL)CYTOSINE HYDROCHLORIDE [J].

HAMAMURA, EK ;

PRYSTASZ, M ;

VERHEYDEN, JPH ;

MOFFATT, JG ;

YAMAGUCHI, K ;

UCHIDA, N ;

SATO, K ;

NOMURA, A ;

SHIRATORI, O ;

TAKASE, S ;

KATAGIRI, K .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (05) :654-662

[17]

HASAGAWA A, 1975, CARBOHYDR RES, V45, P19

[18] STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS .7. SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF 6-AMINO-N-ACETYLMURAMYL AND 6-(ACYLAMINO)-N-ACETYLMURAMYL DIPEPTIDES [J].

HASEGAWA, A ;

OKUMURA, H ;

KISO, M ;

AZUMA, I ;

YAMAMURA, Y .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1980, 44 (06) :1309-1313

[19] STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS .5. SYNTHESIS OF N-ACETYL-6-AMINO-6-DEOXYMURAMOL AND N-ACETYL-6-(ACYLAMINO)-6-DEOXYMURAMOYL DIPEPTIDES, AND THEIR IMMUNOADJUVANT ACTIVITIES [J].

HASEGAWA, A ;

OKUMURA, H ;

KISO, M ;

AZUMA, I ;

YAMAMURA, Y .

CARBOHYDRATE RESEARCH, 1980, 79 (01) :C20-C23

[20] ADJUVANT ACTIVITY OF SYNTHETIC N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE AND RELATED COMPOUNDS ON CELL-MEDIATED CYTOTOXICITY IN SYNGENEIC MICE [J].

IGARASHI, T ;

OKADA, M ;

AZUMA, I ;

YAMAMURA, Y .

CELLULAR IMMUNOLOGY, 1977, 34 (02) :270-278

← 1 2 3 4 →