PHAGE DISPLAY OF A HUMAN-ANTIBODY AGAINST CLOSTRIDIUM-TETANI TOXIN

被引：6

作者：

ESPOSITO, G ^{[1
]}

SCARSELLI, E ^{[1
]}

TRABONI, C ^{[1
]}

机构：

[1] IRBM,I-00040 POMEZIA,ITALY

来源：

GENE | 1994年 / 148卷 / 01期

关键词：

RECOMBINANT DNA; PHAGEMID; IMMUNOGLOBULINS; POLYMERASE CHAIN REACTION;

D O I：

10.1016/0378-1119(94)90252-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

9F12, a human antibody capable of neutralising tetanus toxin in an animal model, has been expressed as a Fab fragment in a phagemid system. The nucleotide sequence for the variable domain of both chains has been determined and compared to germline sequences.

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收藏

页码：167 / 168

页数：2

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