IRREVERSIBLE ENZYME INHIBITORS .70. CANDIDATE ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE .4. SUBSTITUTED 1-PHENYL-1,2-DIHYDRO-S-TRIAZINES

被引：7

作者：

BAKER, BR

HO, BT

机构：

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1967年 / 56卷 / 01期

关键词：

D O I：

10.1002/jps.2600560105

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：28 / &

共 24 条

[1]

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[2]

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[4] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

BAKER, BR .

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[5] ANALOGS OF TETRAHYDROFOLIC ACID .27. HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE BY 2-AMINO-4,6-DISUBSTITUTED-5-ALKYLPYRIMIDINES AND 1-ALKYL-4,6-DIAMINO-1,2-DIHYDRO-S-TRIAZINES [J].

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[6]

BAKER BR, 1966, J PHARM SCI, V55, P295

[7] ANALOGS OF TETRAHYDROFOLIC ACID .29. HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE .2. ON MODE OF PHENYL BINDING OF 1-ARYL-4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-S-TRIAZINES [J].

BAKER, BR ;

HO, BT .

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[8] IRREVERSIBLE ENZYME INHIBITORS .68. 2-AMINO-5-(P-BROMOACETAMIDOPHENOXYPROPYL)-6-PHENYL-4-PYRIMIDINOL AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR OF DIHYDROFOLIC REDUCTASE [J].

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[9]

BAKER BR, 1966, J PHARM SCI, V55, P1417, DOI 10.1002/jps.2600551218

[10] ANALOGS OF TETRAHYDROFOLOC ACID 32 - HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE .V. INHIBITION BY SOME PYRIMIDINES BRIDGED TO BENZOIC ACID [J].

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COWARD, JK ;

SANTI, DV .

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