PHASE-I TRIAL AND PHARMACOKINETIC STUDIES OF ALPHA-DIFLUOROMETHYLORNITHINE - AN INHIBITOR OF POLYAMINE BIOSYNTHESIS

被引：154

作者：

ABELOFF, MD

SLAVIK, M

LUK, GD

GRIFFIN, CA

HERMANN, J

BLANC, O

SJOERDSMA, A

BAYLIN, SB

机构：

[1] UNIV NEW MEXICO,ALBUQUERQUE,NM 87131

[2] MERRELL DOW PHARMACEUT INC,MERRELL RES CTR,CINCINNATI,OH 45215

来源：

JOURNAL OF CLINICAL ONCOLOGY | 1984年 / 2卷 / 02期

关键词：

D O I：

10.1200/JCO.1984.2.2.124

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：124 / 130

页数：7

共 21 条

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[7]

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[8] POLYAMINES ARE NECESSARY FOR THE SURVIVAL OF HUMAN SMALL-CELL LUNG-CARCINOMA IN CULTURE [J].

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[9] ANTI-PROLIFERATIVE PROPERTIES OF DL-ALPHA-DIFLUOROMETHYL ORNITHINE IN CULTURED-CELLS - CONSEQUENCE OF IRREVERSIBLE INHIBITION OF ORNITHINE DECARBOXYLASE [J].

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