A RIBONOLACTONE-BASED APPROACH TO THE SYNTHESIS OF 1'-CARBON-SUBSTITUTED THYMINE RIBONUCLEOSIDES

被引：14

作者：

HAYAKAWA, H ^{[1
]}

MIYAZAWA, M ^{[1
]}

TANAKA, H ^{[1
]}

MIYASAKA, T ^{[1
]}

机构：

[1] SHOWA UNIV,SCH PHARMACEUT SCI,SHINAGAWA KU,TOKYO 142,JAPAN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 1-3期

关键词：

D O I：

10.1080/15257779408013242

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Thymine ribonucleosides bearing a carbon substituent at the anomeric position were synthesized starting from D-ribonolactone by way of nucleophilic addition reaction of organolithium reagents and subsequent condensation with trimethylsilylated thymine.

引用

页码：297 / 308

页数：12

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