USE OF CAPILLARY ELECTROPHORESIS FOR THE DETERMINATION OF VITAMINS OF THE B-GROUP IN PHARMACEUTICAL PREPARATIONS

被引：59

作者：

BOONKERD, S ^{[1
]}

DETAEVERNIER, MR ^{[1
]}

MICHOTTE, Y ^{[1
]}

机构：

[1] FREE UNIV BRUSSELS,INST PHARMACEUT,DEPT PHARMACEUT CHEM & DRUG ANAL,B-1090 JETTE,BELGIUM

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 670卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(94)80296-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The separation of four water-soluble vitamins, i.e., thiamine, riboflavine, pyridoxine and nicotinamide, was investigated by capillary zone electrophoresis and micellar electrokinetic chromatography. The usefulness of the internal standard technique in order to improve the precision of peak area when either the migration time or the injection volume varied was demonstrated. Quantitative analyses of different pharmaceutical formulations were compared with the LC method of the US Pharmacopeia. A good correlation was obtained.

引用

页码：209 / 214

页数：6