BACTEREMIA INVOLVING THE STREPTOCOCCUS-MILLERI GROUP - ANALYSIS OF 19 CASES

被引:57
作者
JACOBS, JA [1 ]
PIETERSEN, HG [1 ]
STOBBERINGH, EE [1 ]
SOETERS, PB [1 ]
机构
[1] UNIV LIMBURG HOSP,DEPT SURG,MAASTRICHT,NETHERLANDS
关键词
D O I
10.1093/clinids/19.4.704
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
During a 3-year study period, 19 patients at the University Hospital of Maastricht developed bloodstream infections with species ofthe ''Streptococcus milleri'' group, for an incidence of 0.33 per 1,000 admissions. The patients' median age was 48 years; the male-to-female ratio was 2.8. Eleven patients (57.9%) had underlying diseases, among which malignancy was predominant. Local trauma to the mucosal barrier was an important risk factor. An associated site of infection was found most frequently in the abdominal and thoracic cavities (nine and five cases, respectively). Bacteremia was polymicrobial in four of 19 episodes. The 20 infecting S. milleri strains were identified to the species level; Streptococcus anginosus was the most prevalent (16 strains). Eight strains carried Lancefield group C. The isolates were sensitive to most antibiotics. Abscess formation was documented in nine cases (47.3%); repeated drainage procedures were required in half of these episodes. Mortality was high (five of 19 patients, or 26.3%).
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页码:704 / 713
页数:10
相关论文
共 40 条
[11]  
GELFAND MS, 1989, REV INFECT DIS, V11, P983
[12]  
GOSSLING J, 1988, REV INFECT DIS, V10, P257
[13]  
Lennette E.H., 1980, MANUAL CLIN MICROBIO, P195
[14]  
LEPENNEC MP, 1989, J ANTIMICROB CHEMOTH, V24, P618
[15]   STREPTOCOCCUS-MILLERI ENDOCARDITIS COMPLICATED BY MYOCARDIAL ABSCESS [J].
LEVANDOWSKI, RA .
SOUTHERN MEDICAL JOURNAL, 1985, 78 (07) :892-893
[16]  
LIBERTIN CR, 1985, REV INFECT DIS, V7, P498
[17]  
MEYES E, 1990, J RHEUMATOL, V17, P1421
[18]  
MILLER SD, 1983, S AFR MED J, V63, P684
[19]   SERIOUS INFECTIONS CAUSED BY STREPTOCOCCUS MILLERI [J].
MURRAY, HW ;
GROSS, KC ;
MASUR, H ;
ROBERTS, RB .
AMERICAN JOURNAL OF MEDICINE, 1978, 64 (05) :759-764
[20]   STREPTOCOCCI AND AEROCOCCI ASSOCIATED WITH SYSTEMIC INFECTION IN MAN [J].
PARKER, MT ;
BALL, LC .
JOURNAL OF MEDICAL MICROBIOLOGY, 1976, 9 (03) :275-302