MOLECULAR ENZYMOLOGY OF THE REDUCTIVE BIOACTIVATION OF HYPOXIC CELL CYTOTOXINS

被引：69

作者：

WALTON, MI ^{[1
]}

WOLF, CR ^{[1
]}

WORKMAN, P ^{[1
]}

机构：

[1] IMPERIAL CANC RES FUND,MOLEC PHARMACOL & DRUG METAB LAB,EDINBURGH EH8 9XD,SCOTLAND

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1989年 / 16卷 / 04期

关键词：

D O I：

10.1016/0360-3016(89)90900-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：983 / 986

页数：4

共 22 条

[1] STABILITY OF SUSPENSIONS OF RAT-LIVER MICROSOMES QUICK-FROZEN WITH LIQUID-NITROGEN AND STORED AT -85 DEGREES [J].

BORTON, P ;

CARSON, R ;

REED, DJ .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (16) :2332-2334

[2] NITROIMIDAZOLES AS ANAEROBIC ELECTRON-ACCEPTORS FOR XANTHINE-OXIDASE [J].

CLARKE, ED ;

GOULDING, KH ;

WARDMAN, P .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (20) :3237-3242

[3] PREPARATION AND PROPERTIES OF MICROSOMAL FRACTIONS [J].

ERIKSSON, LC ;

DEPIERRE, JW ;

DALLNER, G .

PHARMACOLOGY & THERAPEUTICS PART A-CHEMOTHERAPY TOXICOLOGY AND METABOLIC INHIBITORS, 1978, 2 (02) :281-317

[4] MISONIDAZOLE AND OTHER HYPOXIA MARKERS - METABOLISM AND APPLICATIONS [J].

FRANKO, AJ .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1986, 12 (07) :1195-1202

[5]

GILLETTE JR, 1986, MOL PHARMACOL, V4, P541

[6] PARTICIPATION OF CYTOCHROME-P-450 IN THE REDUCTION OF NITRO-COMPOUNDS BY RAT-LIVER MICROSOMES [J].

HARADA, N ;

OMURA, T .

JOURNAL OF BIOCHEMISTRY, 1980, 87 (05) :1539-1554

[7]

Hewick DS, 1982, METABOLIC BASIS DETO, P151

[8]

KATO R, 1978, MOL PHARMACOL, V14, P654

[9] MOLECULAR MECHANISMS FOR THE HYPOXIA-DEPENDENT ACTIVATION OF 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE (SR-4233) [J].

LADEROUTE, K ;

WARDMAN, P ;

RAUTH, AM .

BIOCHEMICAL PHARMACOLOGY, 1988, 37 (08) :1487-1495

[10] IDENTIFICATION OF 2 MAJOR REDUCTION PRODUCTS OF THE HYPOXIC CELL TOXIN 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE [J].

LADEROUTE, KR ;

RAUTH, AM .

BIOCHEMICAL PHARMACOLOGY, 1986, 35 (19) :3417-3420

← 1 2 3 →