ANALYSIS OF MHC-PRESENTED PEPTIDES - APPLICATIONS IN AUTOIMMUNITY AND VACCINE DEVELOPMENT

被引：35

作者：

CHICZ, RM ^{[1
]}

URBAN, RG ^{[1
]}

机构：

[1] HARVARD UNIV,DEPT BIOCHEM & MOLEC BIOL,CAMBRIDGE,MA 02138

来源：

IMMUNOLOGY TODAY | 1994年 / 15卷 / 04期

关键词：

D O I：

10.1016/0167-5699(94)90311-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T cells recognize antigenic peptides presented on the cell surface by major histocompatibility complex (MHC) molecules. Here, Roman Chicz and Robert Urban describe the features of peptides bound to MHC molecules and the mechanism by which these surface proteins bind diverse peptide ligands with high affinity. In addition, they discuss the application of new technologies to the identification of MHC-associated peptides.

引用

页码：155 / 160

页数：6

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