SILICA-BONDED CHIRAL STATIONARY PHASES WITH STRUCTURALLY SIMPLE PI-DONOR CHIRAL SELECTORS FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：27

作者：

OLIVEROS, L

MINGUILLON, C

DESMAZIERES, B

DESBENE, PL

机构：

[1] UNIV PARIS 06,CHIM ORGAN STRUCT LAB,URA 455,F-75230 PARIS 05,FRANCE

[2] UNIV ROUEN HAUTE NORMANDIE,LASOC,F-27000 EVREUX,FRANCE

来源：

JOURNAL OF CHROMATOGRAPHY | 1992年 / 589卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(92)80005-F

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Seven new chiral stationary phases obtained from (S)-phenylalanine derivatives, (R)-Mosher's acid and (S)-naproxen were prepared and evaluated. The racemic substances used to test them contained either pi-acidic or pi-basic sites. The best results were observed when the chiral entity bonded to gamma-aminopropylsilica gel was 3,5-dimethylanilido-, 3,5-dimethylbenzoyl- or 3,5-dimethoxybenzoyl-(S)-phenylalanine and -(S)-naproxen.

引用

页码：53 / 59

页数：7