A CONVENIENT SYNTHESIS OF N-BOC PROTECTED PRIMARY AMINES VIA THE REACTION OF ORGANOBORANES WITH LI OR K TERT-BUTYL-N-TOSYLOXYCARBAMATE

被引：17

作者：

GENET, JP

HAJICEK, J

BISCHOFF, L

GRECK, C

机构：

[1] Laboratoire de Synthese Organique Associe au CNRS-Ecole Nationale Superieure de Chimie de Paris, 75231 Paris Cedex 05, 11, rue Pierre et Marie Curie

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 19期

关键词：

AMINATION; ORGANOBORANES; TERT-BUTYL-N-TOSYLOXYCARBAMATE;

D O I：

10.1016/S0040-4039(00)79055-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Primary and secondary alkylboranes reacted rapidly at low temperature with Li or K t-butyl-N-tosyloxycarbamate (LiBTOC or KBTOC) to give the corresponding N-Boc protected primary amines in modest to good yields (16-81%).

引用

页码：2677 / 2680

页数：4

共 23 条

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