PURIFICATION AND CHARACTERIZATION OF CYTOCHROME-P-450SCA FROM STREPTOMYCES-CARBOPHILUS - ML-236B (COMPACTIN) INDUCES A CYTOCHROME-P-450SCA IN STREPTOMYCES-CARBOPHILUS THAT HYDROXYLATES ML-236B TO PRAVASTATIN SODIUM (CS-514), A TISSUE-SELECTIVE INHIBITOR OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE5

被引：87

作者：

MATSUOKA, T ^{[1
]}

MIYAKOSHI, S ^{[1
]}

TANZAWA, K ^{[1
]}

NAKAHARA, K ^{[1
]}

HOSOBUCHI, M ^{[1
]}

SERIZAWA, N ^{[1
]}

机构：

[1] SANKYO CO LTD,FERMENTAT RES LABS,2-58 HIROMACHI 1 CHOME,SHINAGAWA KU,TOKYO 140,JAPAN

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1989年 / 184卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1989.tb15070.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：707 / 713

页数：7

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