MICROALBUMINURIA - PROGNOSTIC AND THERAPEUTIC IMPLICATIONS IN DIABETIC AND HYPERTENSIVE PREGNANCY

被引：4

作者：

BAR, J

HOD, M

ERMAN, A

FRIEDMAN, S

OVADIA, Y

机构：

[1] Department of Obstetrics and Gynecology, Tel Aviv University, Tel Aviv

[2] Institute of Nephrology and Hypertension, Beilinson Medical Center, Petah Tiqva

[3] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv

来源：

DIABETIC MEDICINE | 1995年 / 12卷 / 08期

关键词：

MICROALBUMINURIA; PREGNANCY; DIABETES; HYPERTENSION;

D O I：

10.1111/j.1464-5491.1995.tb00564.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Microalbuminuria is defined as urinary excretion of albumin that is persistently above normal, although below the sensitivity of conventional semiquantative test strips. Several studies have reported that Type 1 diabetic patients with microalbuminuria are apparently more likely to develop diabetic nephropathy eventually progressing to renal failure. Microalbuminuria is also a strong predictor of mortality in Type 2 diabetes, and is correlated with increased blood pressure in patients with benign essential hypertension. Radioimmunoassay revealed a significantly higher urinary albumin excretion rate in normal pregnant women in the third trimester of pregnancy, compared to the second and first, and compared to non-pregnant women. Microalbuminuria was found in 30% of women who had a record of gestational diabetes mellitus. Published results are controversial regarding the assumption that microalbuminuria is an early predictor of pregnancy-induced hypertensive complications.

引用

页码：649 / 656

页数：8

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