A HIGHLY SENSITIVE LACTATE EDITING TECHNIQUE FOR SURFACE COIL SPECTROSCOPIC IMAGING INVIVO

被引：11

作者：

BOURGEOIS, D ^{[1
]}

KOZLOWSKI, P ^{[1
]}

机构：

[1] NATL RES COUNCIL CANADA,INST BIODIAGNOST,OTTAWA K1A 0R6,ONTARIO,CANADA

来源：

MAGNETIC RESONANCE IN MEDICINE | 1993年 / 29卷 / 03期

关键词：

NMR SPECTROSCOPY; PULSE SEQUENCES; LACTATE EDITING; SURFACE COIL;

D O I：

10.1002/mrm.1910290320

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A lactate editing sequence based on the use of spin‐locking pulses with surface coils is described. The sequence retains more than 90% of the available lactate magnetization and suppresses at least 95% of the lipid signal in a single scan and ca. 99.5% after a simple two step cycle. The technique allows simultaneous observation of lactate and uncoupled metabolites in the range 2 to 3 ppm. The sequence was combined with two‐dimensional spectroscopic imaging to obtain a lactate map of an ischemic rat brain in vivo. Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company

引用

页码：402 / 406

页数：5

共 38 条

[1] ABSORPTION-SPECTRA FROM PHASE-MODULATED SPIN ECHOES
BAX, A
MEHLKOPF, AF
SMIDT, J
[J]. JOURNAL OF MAGNETIC RESONANCE, 1979, 35 (03) : 373 - 377
[2] ASSIGNMENT OF RESONANCES IN THE H-1 SPECTRUM OF RAT-BRAIN BY 2-DIMENSIONAL SHIFT CORRELATED AND J-RESOLVED NMR-SPECTROSCOPY
BEHAR, KL
OGINO, T
[J]. MAGNETIC RESONANCE IN MEDICINE, 1991, 17 (02) : 285 - 303
[3] BENDALL MR, 1983, J MAGN RESON, V53, P365, DOI 10.1016/0022-2364(83)90211-1
[4] WATER-SUPPRESSING PULSE SEQUENCE FOR INVIVO H-1-NMR SPECTROSCOPY WITH SURFACE COILS
BLONDET, P
DECORPS, M
ALBRAND, JP
BENABID, AL
REMY, C
[J]. JOURNAL OF MAGNETIC RESONANCE, 1986, 69 (02) : 403 - 409
[5] PROTON SPECTROSCOPIC IMAGING - A TOOL FOR STUDYING INTRACEREBRAL TUMOR-MODELS IN RAT
BOURGEOIS, D
REMY, C
LEFUR, Y
DEVOULON, P
BENABID, AL
DECORPS, M
[J]. MAGNETIC RESONANCE IN MEDICINE, 1991, 21 (01) : 10 - 20
[6] METABOLITE EDITING VIA CORRELATED 2-ORDER WITH TOTAL INHERENT COHERENCE - ECZOTIC
BRERETON, IM
GALLOWAY, GJ
ROSE, SE
DODDRELL, DM
[J]. JOURNAL OF MAGNETIC RESONANCE, 1989, 83 (01): : 190 - 196
[7] DELAYED AMPA RECEPTOR BLOCKADE REDUCES CEREBRAL INFARCTION INDUCED BY FOCAL ISCHEMIA
BUCHAN, AM
XUE, D
HUANG, ZG
SMITH, KH
LESIUK, H
[J]. NEUROREPORT, 1991, 2 (08) : 473 - 476
[8] CAMPBELL ID, 1975, JCS CHEM COMM, V750
[9] SIGNAL TO NOISE AND SPATIAL LOCALIZATION OF NMR-SPECTRA WITH A SURFACE COIL AND THE SATURATION RECOVERY SEQUENCE
DECORPS, M
LAVAL, M
CONFORT, S
CHAILLOUT, JJ
[J]. JOURNAL OF MAGNETIC RESONANCE, 1985, 61 (03) : 418 - 425
[10] Doddrell D M, 1989, NMR Biomed, V2, P39, DOI 10.1002/nbm.1940020108

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