A HIGHLY SENSITIVE LACTATE EDITING TECHNIQUE FOR SURFACE COIL SPECTROSCOPIC IMAGING INVIVO

被引：11

作者：

BOURGEOIS, D ^{[1
]}

KOZLOWSKI, P ^{[1
]}

机构：

[1] NATL RES COUNCIL CANADA,INST BIODIAGNOST,OTTAWA K1A 0R6,ONTARIO,CANADA

来源：

MAGNETIC RESONANCE IN MEDICINE | 1993年 / 29卷 / 03期

关键词：

NMR SPECTROSCOPY; PULSE SEQUENCES; LACTATE EDITING; SURFACE COIL;

D O I：

10.1002/mrm.1910290320

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A lactate editing sequence based on the use of spin‐locking pulses with surface coils is described. The sequence retains more than 90% of the available lactate magnetization and suppresses at least 95% of the lipid signal in a single scan and ca. 99.5% after a simple two step cycle. The technique allows simultaneous observation of lactate and uncoupled metabolites in the range 2 to 3 ppm. The sequence was combined with two‐dimensional spectroscopic imaging to obtain a lactate map of an ischemic rat brain in vivo. Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company

引用

页码：402 / 406

页数：5

共 38 条

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