CHRONIC MORPHINE-INDUCED HYPERACTIVITY IN RATS IS ALTERED BY NUCLEUS ACCUMBENS AND VENTRAL TEGMENTAL LESIONS

被引：29

作者：

BUNNEY, WC

MASSARI, VJ

PERT, A

机构：

[1] NIMH, BIOL PSYCHIAT BRANCH, BIOCHEM & PHARMACOL SECT, BETHESDA, MD 20205 USA

[2] HOWARD UNIV, DEPT PHARMACOL, WASHINGTON, DC 20059 USA

来源：

PSYCHOPHARMACOLOGY | 1984年 / 82卷 / 04期

关键词：

D O I：

10.1007/BF00427677

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Lesions of the nucleus accumbens (NA) and the ventral tegmental area (VTA) attenuated and delayed the onset of the locomotor excitatory effects of morphine following chronic administration. Neither lesion totally prevented the increase in locomotor excitation. While the NA and VTA seem to play a role in mediating the excitatory effects of morphine, other regions and brain circuits may also be involved.

引用

页码：318 / 321

页数：4

共 18 条

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