A COMPARISON OF THE ANTIVIRAL AGENTS 2'-NOR-2'-DEOXYGUANOSINE AND ACYCLOVIR - UPTAKE AND PHOSPHORYLATION IN TISSUE-CULTURE AND KINETICS OF INVITRO INHIBITION OF VIRAL AND CELLULAR DNA-POLYMERASES BY THEIR RESPECTIVE TRIPHOSPHATES

被引：47

作者：

GERMERSHAUSEN, J ^{[1
]}

BOSTEDOR, R ^{[1
]}

FIELD, AK ^{[1
]}

PERRY, H ^{[1
]}

LIOU, R ^{[1
]}

BULL, H ^{[1
]}

TOLMAN, RL ^{[1
]}

KARKAS, JD ^{[1
]}

机构：

[1] MERCK SHARP & DOHME,RES LAB,W POINT,PA 19486

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1983年 / 116卷 / 02期

关键词：

D O I：

10.1016/0006-291X(83)90530-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：360 / 367

页数：8

共 12 条

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[3]

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[4]

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[5] 9-([2-HYDROXY-1-(HYDROXYMETHYL)ETHOXY]METHYL)GUANINE - A SELECTIVE INHIBITOR OF HERPES GROUP VIRUS-REPLICATION [J].

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DAVIES, ME ;

DEWITT, C ;

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[6] INHIBITION OF HERPES-SIMPLEX VIRUS-INDUCED DNA-POLYMERASE ACTIVITY AND VIRAL-DNA REPLICATION BY 9-(2-HYDROXYETHOXYMETHYL)GUANINE AND ITS TRIPHOSPHATE [J].

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[7]

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[8] PURIFICATION OF POTASSIUM PHOSPHATE FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

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[9] PROPERTIES OF HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 DNA-POLYMERASE [J].

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[10]

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