ELECTROCHEMICAL MODELS FOR CYTOCHROME-P-450 - N-DEMETHYLATION OF TERTIARY AMIDES BY ANODIC-OXIDATION

被引：61

作者：

HALL, LR

IWAMOTO, RT

HANZLIK, RP

机构：

[1] UNIV KANSAS,DEPT MED CHEM,LAWRENCE,KS 66045

[2] UNIV KANSAS,DEPT CHEM,LAWRENCE,KS 66045

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1989年 / 54卷 / 10期

关键词：

D O I：

10.1021/jo00271a040

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

收藏

页码：2446 / 2451

页数：6

相关论文

共 45 条

[1] AGUSTO O, 1982, J BIOL CHEM, V257, P11288
[2] DEALKYLATION OF SOME PARA-NITROPHENYLALKYLETHERS AND THEIR ALPHA-DEUTERATED ANALOGS BY RAT-LIVER MICROSOMES
ALGAILANY, KAS
BRIDGES, JW
NETTER, KJ
[J]. BIOCHEMICAL PHARMACOLOGY, 1975, 24 (08) : 867 - 870
[3] BACIOCCHI E, 1980, J AM CHEM SOC, V102, P7598
[4] MECHANISM OF CYTOCHROME-P-450 CATALYSIS - MECHANISM OF N-DEALKYLATION AND AMINE OXIDE DEOXYGENATION
BURKA, LT
GUENGERICH, FP
WILLARD, RJ
MACDONALD, TL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (08) : 2549 - 2551
[5] DEUTERIUM-ISOTOPE EFFECTS IN INVIVO METABOLISM OF COTININE
DAGNE, E
GRUENKE, L
CASTAGNOLI, N
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (12) : 1330 - 1333
[6] EFFECT OF DEUTERATION OF N-CH3 GROUP ON POTENCY AND ENZYMATIC N-DEMETHYLATION OF MORPHINE
ELISON, C
ELLIOTT, HW
LAURSEN, R
RAPOPORT, H
[J]. SCIENCE, 1961, 134 (348) : 1078 - &
[7] Foster A.B., 1985, ADV DRUG RES, V14, P2
[8] ISOTOPE-EFFECTS IN O-DEMETHYLATIONS MEDIATED BY RAT-LIVER MICROSOMES - APPLICATION OF DIRECT INSERTION ELECTRON-IMPACT MASS-SPECTROMETRY
FOSTER, AB
JARMAN, M
STEVENS, JD
THOMAS, P
WESTWOOD, JH
[J]. CHEMICO-BIOLOGICAL INTERACTIONS, 1974, 9 (05) : 327 - 340
[9] GRAMAIN JC, 1982, SYNTHESIS-STUTTGART, P264
[10] GUENGERICH FP, 1987, J BIOL CHEM, V262, P8459

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