ALTERED MUROPEPTIDE COMPOSITION IN STAPHYLOCOCCUS-AUREUS STRAINS WITH AN INACTIVATED FEMA LOCUS

被引：78

作者：

DEJONGE, BLM

SIDOW, T

CHANG, YS

LABISCHINSKI, H

BERGERBACHI, B

GAGE, DA

TOMASZ, A

机构：

[1] MICHIGAN STATE UNIV,MSU NIH MASS SPECTR FACIL,DEPT BIOCHEM,E LANSING,MI 48824

[2] FED HLTH OFF,ROBERT KOCH INST,W-1000 BERLIN 65,GERMANY

[3] ROCKEFELLER UNIV,NEW YORK,NY 10021

[4] UNIV ZURICH,INST MED MICROBIOL,CH-8028 ZURICH,SWITZERLAND

来源：

JOURNAL OF BACTERIOLOGY | 1993年 / 175卷 / 09期

关键词：

D O I：

10.1128/JB.175.9.2779-2782.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Tn551 inactivation of femA, a factor involved in methicillin resistance of Staphylococcus aureus, caused the production of peptidoglycan in which the fraction of monoglycyl- and serine-containing muropeptides was increased at the expense of pentaglycyl muropeptides. femA mutants have a specific block in the biosynthesis of pentaglycine cross bridges after the addition of the first glycine residue.

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页码：2779 / 2782

页数：4

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