URINARY INDOLEAMINES IN TOURETTE SYNDROME PATIENTS WITH OBSESSIVE-COMPULSIVE CHARACTERISTICS

被引：13

作者：

BORNSTEIN, RA ^{[1
]}

BAKER, GB ^{[1
]}

机构：

[1] UNIV ALBERTA, DEPT PSYCHIAT, NEUROCHEM RES UNIT, EDMONTON T6G 2E1, ALBERTA, CANADA

来源：

PSYCHIATRY RESEARCH | 1992年 / 41卷 / 03期

关键词：

GILLES-DE-LA-TOURETTE SYNDROME; SEROTONIN; 5-HYDROXYINDOLEACETIC ACID; TRYPTAMINE; INDOLE-3-ACETIC ACID;

D O I：

10.1016/0165-1781(92)90008-Q

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Tourette syndrome patients with high levels of obsessive-compulsive symptoms were compared with patients without these symptoms on urinary measures of serotonin and its major metabolite, 5-hydroxyindoleacetic acid (5HIAA). Both groups were compared with normal controls, and it was hypothesized that patients with obsessive-compulsive symptoms would have lower levels of serotonin. Both groups of Tourette syndrome patients had lower levels than controls, but there was no difference between them. Obsessive symptoms were related to higher levels of 5HIAA and to a higher turnover of serotonin.

引用

页码：267 / 274

页数：8

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