MINOR BREAKPOINT CLUSTER REGION (M-BCR) POSITIVE CHRONIC MYELOID-LEUKEMIA WITH AN ACUTE LYMPHOBLASTIC-LEUKEMIA ONSET - A CASE-REPORT

m-BCR chronic myeloid leukaemia (CML) is a rare entity. We report a patient presenting with Philadelphia (Ph)-positive, m-BCR-positive acute lymphoblastic leukaemia (ALL) who achieved complete remission after induction chemotherapy, but showed a majority of Ph-positive mitoses during this remission, A diagnosis of m-BCR CML was established and the patient was given interferon a therapy. This is the first m-BCR CML presenting as ab initio ALL. This report emphasizes the importance of karyotyping Ph-positive ALL during remission so as not to misdiagnose CML patients who can benefit from Interferon therapy.