CROSSTALK BETWEEN CALCIUM-MEDIATED AND CYCLIC AMP-MEDIATED SIGNALING SYSTEMS AND THE SHORT-TERM MODULATION OF BILE-FLOW IN NORMAL AND CHOLESTATIC RAT-LIVER

被引：11

作者：

BYGRAVE, FL ^{[1
]}

KARJALAINEN, A ^{[1
]}

HAMADA, Y ^{[1
]}

机构：

[1] NATL NISHI SAPPORO HOSP,DEPT GASTROENTEROL,NISHI KU,SAPPORO,HOKKAIDO 063,JAPAN

来源：

CELLULAR SIGNALLING | 1994年 / 6卷 / 01期

关键词：

BILE FLOW; GLUCAGON; VASOPRESSIN; CROSSTALK; CALCIUM; CHOLESTASIS;

D O I：

10.1016/0898-6568(94)90055-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The flow of bile is subject to short-term modulation by glucagon and calcium-mobilizing hormones. Of potential relevance is the crosstalk between the second messenger-mediated signal transducing systems of these agonists. This latter point has revealed an area of investigation that should enable further insights to be made into a physiological network that interrelates bile flow, hepatocellular calcium movements and hormone action. This information in turn may provide insights into the etiology and treatment of human and animal diseases in which cholestasis is an underlying feature.

引用

页码：1 / 9

页数：9

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